Common Use
Dicaris (levamisole) is an anthelmintic and immunomodulatory medication used to treat parasitic worm infections (helminthiases) and, in certain clinical settings, to support immune system function. As an anthelmintic, Dicaris is highly effective against roundworm (Ascaris lumbricoides) infections and is also used to treat hookworm (Ancylostoma duodenale, Necator americanus) and other susceptible intestinal nematode infestations. Levamisole works by paralyzing the worm's muscles through depolarizing neuromuscular blockade, causing the parasites to lose their ability to attach to the intestinal wall and be expelled naturally through bowel movements. Beyond its antiparasitic action, levamisole has unique immunomodulatory properties — it enhances cell-mediated immunity by stimulating T-lymphocyte function, restoring depressed immune responses, and modulating macrophage activity. This dual action makes Dicaris valuable not only for deworming but also as an adjunctive immunostimulant in conditions such as recurrent infections, certain autoimmune conditions, and as adjuvant therapy in some oncological protocols (under strict medical supervision). If you want to buy Dicaris online for parasite treatment or immune support, always use a licensed pharmacy and consult a healthcare professional.

Dosage and Direction
The dosage of Dicaris depends on the age, body weight, and the type of infection being treated. For adults with roundworm infection, the standard dose is 150 mg (one tablet) taken as a single oral dose, preferably in the evening after a meal. For children, the dose is calculated based on body weight — typically 2.5 mg per kg of body weight as a single dose. Dicaris 50 mg tablets are available for pediatric use. For hookworm and other nematode infections, the same single-dose regimen is usually effective, though your doctor may prescribe a repeated dose after 7 to 14 days to ensure complete eradication. When used as an immunomodulator, the dosing schedule is different — typically 150 mg once weekly or on a specific intermittent schedule as determined by the treating physician. Swallow the tablet whole with water. Do not crush or chew. Follow the dosage schedule provided by your doctor precisely, and do not self-adjust the dose.

Precautions
Before using Dicaris, inform your doctor if you have liver disease, kidney problems, blood disorders (especially leukopenia or agranulocytosis), or any autoimmune conditions. Regular monitoring of complete blood counts (CBC) is recommended, particularly when levamisole is used as an immunomodulator or for extended periods, as the medication may cause reversible leukopenia or, rarely, agranulocytosis. Watch for any unusual symptoms such as persistent unexplained fever, sore throat, mouth ulcers, or unusual bruising, which may indicate blood cell abnormalities. Avoid self-medicating and always complete the prescribed course. Alcohol should be avoided on the day of taking Dicaris and for at least 24 hours afterward, as a disulfiram-like reaction (nausea, vomiting, flushing, tachycardia) may occur. Use during pregnancy and breastfeeding should be avoided unless the physician determines that the benefit outweighs the risk.

Contraindications
Dicaris is contraindicated in patients with known hypersensitivity to levamisole or any excipient in the formulation. It should not be used in patients with pre-existing agranulocytosis or severe leukopenia, as levamisole may further suppress white blood cell production. Patients with severe hepatic impairment should avoid this medication. Use during pregnancy is generally not recommended, particularly during the first trimester, and breastfeeding mothers should consult their physician before use. Children under the age of 3 years should not be given Dicaris without specific medical advice. Patients with a history of hypersensitivity vasculitis or levamisole-induced adverse reactions should not use this drug.

Possible Side Effects
Common side effects of Dicaris include mild nausea, vomiting, diarrhea, abdominal cramps, headache, and dizziness — these are generally transient and resolve within 24 hours of the single-dose treatment. Some patients may notice an altered sense of taste or smell. Less common side effects include skin rash, urticaria (hives), or muscle aches. Rare but serious adverse effects include leukopenia (low white blood cell count), agranulocytosis (severe reduction in granulocytes), thrombocytopenia, and encephalopathy-like syndrome (presenting as confusion, seizures, or speech disturbances) — these are more commonly associated with prolonged immunomodulatory use. Seek immediate medical attention if you experience severe skin reactions, persistent high fever, unexplained bruising or bleeding, or neurological symptoms.

Drug Interaction
Dicaris may interact with several types of medications. Concurrent use with immunosuppressive drugs (such as corticosteroids or cytotoxic agents) may alter the immune-modulating effects of levamisole. Drugs that affect bone marrow function or blood cell counts should be used with caution alongside Dicaris. Alcohol must be avoided due to the risk of disulfiram-like reactions. Levamisole may increase the anticoagulant effect of warfarin, requiring INR monitoring and dose adjustments. Concurrent use with phenytoin may increase phenytoin blood levels. Always inform your healthcare provider about all prescription and over-the-counter medications, vitamins, and herbal supplements you are taking before using Dicaris.

Missed Dose
Since Dicaris is typically taken as a single dose for parasitic infections, a missed dose is uncommon. If you forget to take your scheduled dose, take it as soon as you remember. If you are on a weekly immunomodulatory regimen and miss a dose, take it as soon as you remember, but do not take a double dose. Continue with your regular schedule and inform your doctor at the next visit.

Overdose
Overdose of Dicaris may cause nausea, vomiting, dizziness, drowsiness, diarrhea, and in more serious cases, hematological abnormalities (leukopenia, agranulocytosis) or neurological disturbances (confusion, tremors, seizures). There is no specific antidote for levamisole overdose. Seek immediate medical attention if an overdose is suspected. Treatment is supportive and symptomatic, including gastric lavage if performed soon after ingestion, monitoring of blood counts, and supportive care for any neurological symptoms.

Storage
Store Dicaris at controlled room temperature between 15°C and 25°C (59°F to 77°F), away from excessive heat, moisture, and direct sunlight. Keep the tablets in their original packaging. Keep out of reach of children. Do not use after the expiration date printed on the package.

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.